It was revealed a new mechanism for harmful effects of nicotine on the human brain. A group of scientists from Medical school at northwestern University Feinberg (USA) made in connection with this new discovery.
A team of researchers led by Professor of pharmacology Ryan Drenan discovered additional areas of the brain responsible for the formation of human dependency. Scientists say that this will allow science and medicine to better understand the algorithm of formation of nicotine addiction. In particular, the researchers found that receptors in the nicotine-sensitive acetylcholine receptors (nAChRs) functionally have a connection with the neurons of the hypothalamus.
“Identification of the detailed mechanisms by which nicotine changes the scheme of work of the brain, is extremely important. We have expanded opportunities for drug development to combat Smoking and drug addiction. The study results improve the understanding of how neurotransmitters work in the brain,” said the authors.
As follows from the studies, nicotine stimulates the dopamine receptors and the GABA neurons. For some time, the stimulation causes a state of euphoria, but then there is addictive. This work suggests that brain regions more involved in the process of forming a dependency.
According to scientists, the formation of dependence is associated with impaired transmission of dopamine signals. If you restore communication, strengthening the relationship, it is possible to get rid of bad habits, admit scientific specialists.
Prior to this, scientists representing La Trobe University in Australia, found that the substance contained in tobacco, can be useful against infectious diseases, including those that are caused by a very dangerous virus, gold aureus, HIV, zika virus and encephalitis viruses.